Prof. Dr. rer. nat. Martin Kircher

D. Reich, R. Green, M. Kircher, J. Krause, N. Patterson, E. Durand, B. Viola, A. Briggs, U. Stenzel, P. Johnson, T. Maricic, J. Good, T. Marques-Bonet, C. Alkan, Q. Fu, S. Mallick, H. Li, M. Meyer, E. Eichler, M. Stoneking, M. Richards, S. Talamo, M. Shunkov, A. Derevianko, J. Hublin, J. Kelso, M. Slatkin, and S. Pääbo,
Genetic history of an archaic hominin group from Denisova Cave in Siberia, Nature , vol. 468, no. 7327, pp. 1053-1060.

DOI:	10.1038/nature09710

P. Kleinert, and M. Kircher,
A framework to score the effects of structural variants in health and disease, Genome Res , vol. 32, no. 4, pp. 766-777, 2022.

DOI:	10.1101/gr.275995.121

P. Rentzsch, M. Schubach, J. Shendure, and M. Kircher,
CADD-Splice-improving genome-wide variant effect prediction using deep learning-derived splice scores, Genome Med , vol. 13, no. 1, pp. 31, 2021.

DOI:	10.1186/s13073-021-00835-9

M. Kircher, C. Xiong, B. Martin, M. Schubach, F. Inoue, R. Bell, J. Costello, J. Shendure, and N. Ahituv,
Saturation mutagenesis of twenty disease-associated regulatory elements at single base-pair resolution, Nat Commun , vol. 10, no. 1, pp. 3583, 2019.

DOI:	10.1038/s41467-019-11526-w

F. Inoue, M. Kircher, B. Martin, G. Cooper, D. Witten, M. McManus, N. Ahituv, and J. Shendure,
A systematic comparison reveals substantial differences in chromosomal versus episomal encoding of enhancer activity, Genome Res , vol. 27, no. 1, pp. 38-52, 2017.

DOI:	10.1101/gr.212092.116

M. Snyder, M. Kircher, A. Hill, R. Daza, and J. Shendure,
Cell-free DNA Comprises an In Vivo Nucleosome Footprint that Informs Its Tissues-Of-Origin, Cell , vol. 164, no. 1-2, pp. 57-68, 2016.

DOI:	10.1016/j.cell.2015.11.050

M. Kircher, D. Witten, P. Jain, B. O'Roak, G. Cooper, and J. Shendure,
A general framework for estimating the relative pathogenicity of human genetic variants, Nat Genet , vol. 46, no. 3, pp. 310-5, 2014.

DOI:	10.1038/ng.2892

M. Meyer, M. Kircher, M. Gansauge, H. Li, F. Racimo, S. Mallick, J. Schraiber, F. Jay, K. Prufer, C. Filippo, P. Sudmant, C. Alkan, Q. Fu, R. Do, N. Rohland, A. Tandon, M. Siebauer, R. Green, K. Bryc, A. Briggs, U. Stenzel, J. Dabney, J. Shendure, J. Kitzman, M. Hammer, M. Shunkov, A. Derevianko, N. Patterson, A. Andres, E. Eichler, M. Slatkin, D. Reich, J. Kelso, and S. Paabo,
A high-coverage genome sequence from an archaic Denisovan individual, Science , vol. 338, no. 6104, pp. 222-6, 2012.

DOI:	10.1126/science.1224344

M. Kircher, S. Sawyer, and M. Meyer,
Double indexing overcomes inaccuracies in multiplex sequencing on the Illumina platform, Nucleic Acids Res , vol. 40, no. 1, pp. e3, 2012.

DOI:	10.1093/nar/gkr771

M. Kircher, U. Stenzel, and J. Kelso,
Improved base calling for the Illumina Genome Analyzer using machine learning strategies, Genome Biol , vol. 10, no. 8, pp. R83, 2009.

DOI:	10.1186/gb-2009-10-8-r83