Dr. rer. nat. Alexandra Kulle

Photo of Alexandra  Kulle

Klinik für Kinder- und Jugendmedizin I
Quincke Forschungszentrum


Christian-Albrechts-Universität zu Kiel
Rosalind-Franklin-Straße 9
24105 Kiel

Email: alexandra.kulle(at)uksh.de
Phone: +49 431 500-20230

Publications

A. Seoudy, K. Schlicht, A. Kulle, T. Demetrowitsch, A. Beckmann, C. Geisler, K. Turk, N. Rohmann, K. Hartmann, J. Brandes, D. Schulte, S. Schreiber, K. Schwarz, P. Holterhus, and M. Laudes,
A Prospective Analysis of the Metyrapone Short Test Using Targeted and Untargeted Metabolomics, Neuroendocrinology , 2023.
DOI:10.1159/000529146
R. Hirtz, L. Libuda, A. Hinney, M. Focker, J. Buhlmeier, P. Holterhus, A. Kulle, C. Kiewert, B. Hauffa, J. Hebebrand, and C. Grasemann,
The adrenal steroid profile in adolescent depression: a valuable bio-readout?, Transl Psychiatry , vol. 12, no. 1, pp. 255, 2022.
DOI:10.1038/s41398-022-01966-2
J. Rohayem, M. Zitzmann, S. Laurentino, S. Kliesch, E. Nieschlag, P. Holterhus, and A. Kulle,
The role of gonadotropins in testicular and adrenal androgen biosynthesis pathways—Insights from males with congenital hypogonadotropic hypogonadism on hCG/rFSH and on testosterone replacement, Clinical Endocrinology , vol. 94, no. 1, pp. 90-101, 2021.
DOI:https://doi.org/10.1111/cen.14324
R. Aherrahrou, A. Kulle, N. Alenina, R. Werner, S. Vens-Cappell, M. Bader, H. Schunkert, J. Erdmann, and Z. Aherrahrou,
CYP17A1 deficient XY mice display susceptibility to atherosclerosis, altered lipidomic profile and atypical sex development, Sci Rep , vol. 10, no. 1, pp. 8792, 2020.
DOI:10.1038/s41598-020-65601-0
T. Reinehr, A. Kulle, A. Barth, J. Ackermann, N. Lass, and P. Holterhus,
Sex Hormone Profile in Pubertal Boys With Gynecomastia and Pseudogynecomastia, J Clin Endocrinol Metab , vol. 105, no. 4, pp. e1025-e1032, 2020.
DOI:10.1210/clinem/dgaa044
O. Hiort, M. Cools, A. Springer, K. McElreavey, A. Greenfield, S. Wudy, A. Kulle, S. Ahmed, A. Dessens, A. Balsamo, M. Maghnie, M. Bonomi, M. Dattani, L. Persani, L. Audi, C. DSDnet, and R. Gn,
Addressing gaps in care of people with conditions affecting sex development and maturation, Nat Rev Endocrinol , vol. 15, no. 10, pp. 615-622, 2019.
DOI:10.1038/s41574-019-0238-y
W. Birnbaum, L. Marshall, R. Werner, A. Kulle, P. Holterhus, K. Rall, B. Kohler, A. Richter-Unruh, M. Hartmann, S. Wudy, M. Auer, A. Lux, S. Kropf, and O. Hiort,
Oestrogen versus androgen in hormone-replacement therapy for complete androgen insensitivity syndrome: a multicentre, randomised, double-dummy, double-blind crossover trial, Lancet Diabetes Endocrinol , vol. 6, no. 10, pp. 771-780, 2018.
DOI:10.1016/S2213-8587(18)30197-9
A. Kulle, T. Reinehr, G. Simic-Schleicher, N. Hornig, and P. Holterhus,
Determination of 17OHPreg and DHEAS by LC-MS/MS: Impact of Age, Sex, Pubertal Stage, and BMI on the Delta5 Steroid Pathway, J Clin Endocrinol Metab , vol. 102, no. 1, pp. 232-241, 2017.
DOI:10.1210/jc.2016-2849
A. Kulle, N. Krone, P. Holterhus, G. Schuler, R. Greaves, A. Juul, Y. Rijke, M. Hartmann, A. Saba, O. Hiort, S. Wudy, and E. Action,
Steroid hormone analysis in diagnosis and treatment of DSD: position paper of EU COST Action BM 1303 'DSDnet', Eur J Endocrinol , vol. 176, no. 5, pp. P1-P9, 2017.
DOI:10.1530/EJE-16-0953
A. Kulle, F. Riepe, D. Melchior, O. Hiort, and P. Holterhus,
A novel ultrapressure liquid chromatography tandem mass spectrometry method for the simultaneous determination of androstenedione, testosterone, and dihydrotestosterone in pediatric blood samples: age- and sex-specific reference data, J Clin Endocrinol Metab , vol. 95, no. 5, pp. 2399-409, 2010.
DOI:10.1210/jc.2009-1670